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SmartSquirt® Micro-Perfusion System

Perfuse microliter volumes of precious solutions


Programmable dispensing, microinjection, perfusion or spritzing of reproducible microliter volumes. Up to eight solutions are stored in 2.5ml cryo tube reservoirs with easy syringe refill ports. Included pneumatic solenoid valves deliver regulated air pressure to push liquids out of the  SmartSquirt® Perfusion Pencil tip. An AutoMate Scientific (or other) valve controller offers programmable, manual or computer-controlled valve selection for switching which reagent is delivered from the tip. Pulse a valve quickly for microliter delivery, or leave it on longer for constant perfusion. The short delivery path saves expensive reagents. Integrated BackStop check valves prevent backflow found in competing micro-perfusion systems, while special three-way valve design stops liquids quickly. The 0-10psi regulator and air filter require a compressed air or other gas source — bottle, compressor or lab air. Compare to an eight-channel, 10psi Picospritzer™ at a fraction of the price.

SmartSquirt® is registered tradename belonging to AutoMate Scientific Inc.


  • Deliver microliter volumes starting with as little as 100 microliters of precious drugs

  • Minimize cross-contamination with BackStop™ back-flow prevention 

  • Valves and pressure controls in a small box near microscope – no stand necessary


Pneumatic Valve Switching Speed:
Approx. 10-20 ms.

Reservoir Volume:
2.5ml cryo tubes + 1 pressurized 50ml reservoir (3.5 ml cryo tubes available)

Minimum Starting Volume:
Approx. 100 microliters

Flow Rates:
Depend on removable tip size

5 micron filter included on air inlet

Regulator & Gauge:
0-15 psi

Air Inlet Requirements:
30-100 psi of any gas

360µm I.D. PTFE-lined polyimide 30 cm long


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